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Effect of Bacillus anthracis virulence factors on human dendritic cell activation

✍ Scribed by Andrew C. Hahn; C. Rick Lyons; Mary F. Lipscomb

Book ID: 116531860
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 813 KB
Volume: 69
Category: Article
ISSN: 0198-8859
DOI: 10.1016/j.humimm.2008.06.012

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Anthrax is an infectious disease caused by toxigenic strains of the Gram-positive Bacillus anthracis. [1] If inhaled, B. anthracis spores rapidly reach the regional lymphonodes of the lungs, where they germinate and release anthrax toxins. [2] These toxins inhibit the adaptive immune response, there