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Effect of Aqueous Extract of Brickellia veronicaefolia on the Gastrointestinal Tract of Guinea-pig, Rats and Mice

✍ Scribed by R. Martha Perez G.

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 248 KB
Volume: 10
Category: Article
ISSN: 0951-418X
DOI: 10.1002/(sici)1099-1573(199612)10:8<677::aid-ptr799>3.0.co;2-7

No coin nor oath required. For personal study only.

✦ Synopsis

The aqueous extract of Brickellia veronicaefolia inhibited gastric emptying time in rats and intestinal motility in mice, both effects were manifested in a dose-related fashion. The crude extract inhibited the contractions induced by acetylcholine and histamine concentration-dependently in the guinea-pig ileum. In the castor oil diarrhoea test, the extract showed 90% protection from diarrhoea at 150 mg/kg.

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