Effect of antibody to detergent solubilized zonae pellucidae on in vivo and in vitro fertilization in the mouse
β Scribed by Tsunoda, Y. ;Sugie, T.
- Book ID
- 111662877
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1982
- Weight
- 480 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0148-7280
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## Abstract Bivalent (IgG) rabbit antiβmouse zona pellucida antibody completely inhibited fertilization in the mouse. Univalent (Fab) zona antibody did not inhibit the fertilizability of eggs. However, the treatment or injection with antiβrabbit IgG serum inhibited the fertilizability of eggs pretr
## Abstract The fertilization __in vitro__ of mouse eggs with intact zonae pellucidae by mouse cauda epididymal spermatozoa was inhibited in a concentrationβdependent fashion by 3βquinuclidinyl benzilate (QNB), normally used as a specific antagonist for the muscarinic class of cholinergic receptors