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Effect of antibiotics on intestinal absorption in guinea-pigs

✍ Scribed by David S Madge

Book ID
115830924
Publisher
Elsevier Science
Year
1969
Weight
830 KB
Volume
30
Category
Article
ISSN
0010-406X

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Effect of quinidine on the intestinal se
Effect of quinidine on the intestinal secretion of digoxin in guinea pigs
✍ S. G. SchΓ€fer; B. Fichtl; W. Doering πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 250 KB πŸ‘ 2 views

Following i.v. injection of digoxin (1Opg kg-') the ratio between digoxin concentrations in the lumen ofjejunal loops perfused in situ and in plasma (L/P) of guinea pigs increased linearily with time. After 3 h, L/P was 8.7, indicating net secretion of digoxin against a concentration gradient. In qu