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Effect of anti-Ia treatment on the production of anti-DNA antibody by NZB mice

✍ Scribed by Dennis M. Klinman; Michael D. Lefkowitz; Elizabeth S. Raveche; Alfred D. Steinberg


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
674 KB
Volume
16
Category
Article
ISSN
0014-2980

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## Abstract Injection of an anti‐CD8 monoclonal antibody into mice was followed by an increase in the production of immunoglobulins of the IgG~1~, IgG~2a~, and IgG~2b~, but neither the IgG~3~ nor the IgM isotypes. A maximal effect was observed 6 days after administration of 10ΞΌg antibody. However,