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Effect of aminoacyl transfer RNA synthetases on H-5 exchange of specific pyrimidines in transfer RNAs

✍ Scribed by Schoemaker, Hubert J. P.; Schimmel, Paul R.


Book ID
127332185
Publisher
American Chemical Society
Year
1977
Tongue
English
Weight
867 KB
Volume
16
Category
Article
ISSN
0006-2960

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Aminoacyl-tRNA synthetases are capable of converting 5'-ATP into 5',5'-diadenosine tetraphosphate. The reaction reflects the reversal of enzyme-bound aminoacyl-adenylate by ATP instead of PPi. In the case of a few prokaryotic as well as eukaryotic aminoacyl-tRNA synthetases, the initial rate of diad