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Effect of amino acid substitutions and deletions on the thermal stability, the pH stability and unfolding by urea of bovine calbindin D9k

✍ Scribed by Boel WENDT; Theo HOFMANN; Stephen R. MARTIN; Peter BAYLEY; Peter BRODIN; Thomas GRUNDSTRÖM; Eva THULIN; Sara LINSE; Sture FORSÉN


Book ID
115125883
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
669 KB
Volume
175
Category
Article
ISSN
1432-1327

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The significance of two interface arginine residues on the structural integrity of an obligatory dimeric enzyme thymidylate synthase (TS) from Lactobacillus casei was investigated by thermal and chemical denaturation. While the R178F mutant showed apparent stability to thermal denaturation by its de