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Effect of Amiloride on Sodium-Calcium Exchange Activity in Rat Cardiac Myocytes

✍ Scribed by M. Antolini; L. Trevisi; P. Debetto; S. Luciani

Book ID
118770105
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
151 KB
Volume
27
Category
Article
ISSN
1043-6618

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✍ He-Ping Meng; Michael J. B. Kutryk; Grant N. Pierce πŸ“‚ Article πŸ“… 1990 πŸ› Springer 🌐 English βš– 527 KB

The effects of platelet-activating factor (PAF) on Na(+)-dependent calcium uptake in myocardial sarcolemmal vesicles were examined in order to clarify its mechanism of inotropic action on the heart. PAF (40 and 20 microM) significantly inhibited Na(+)-Ca2+ exchange by 61% and 37%, respectively. Both