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Effect of altered tissue binding on the disposition of barbital in the isolated perfused rat liver: Application of the axial dispersion model

โœ Scribed by Chen-Hsi Chou; Malcolm Rowland

Book ID
109388753
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
114 KB
Volume
86
Category
Article
ISSN
0022-3549

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Primaquine disposition in the isolated p
Primaquine disposition in the isolated perfused rat liver: Effect of mefloquine induced bile flow reduction
โœ Michael D. Coleman; Lawrence Fleckenstein; Melvin H. Heiffer ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 524 KB

The disposition of primaquine (0.75 mg, 5 pC1) has been investigated in the isolated perfused rat liver (IPRL) preparation alone and concurrently with mefloquine. In both groups, primaquine concentrations declined exponentially. There were no significant differences between the respective groups in