𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of aging on mitochondrial and nuclear DNA oxidative damage in the heart and brain throughout the life-span of the rat

✍ Scribed by Asunción Herrero; Gustavo Barja

Publisher
Springer Netherlands
Year
2001
Tongue
English
Weight
501 KB
Volume
24
Category
Article
ISSN
0161-9152

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effect of time of restriction on the dec
Effect of time of restriction on the decrease in mitochondrial H2O2 production and oxidative DNA damage in the heart of food-restricted rats
✍ R. Gredilla; M. López-Torres; G. Barja 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 1 views

## Abstract In the present study, the question if medium‐term (4 months) caloric restriction (40%) decreases mitochondrial H~2~O~2~ production and oxidative DNA damage was investigated. Caloric restriction (CR) is the only experimental manipulation that increases maximum life span. Previous long‐te

Redox proteomics in aging rat brain: Inv
Redox proteomics in aging rat brain: Involvement of mitochondrial reduced glutathione status and mitochondrial protein oxidation in the aging process
✍ M. Perluigi; F. Di Domenico; A. Giorgi; M.E. Schininà; R. Coccia; C. Cini; F. Be 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 396 KB

## Abstract Increasing evidence supports the notion that increased oxidative stress is a fundamental cause in the aging process and in neurodegenerative diseases. As a result, a decline in cognitive function is generally associated with brain aging. Reactive oxygen species (ROS) are highly reactive