Both IDDM and NIDDM are characterized by deviations in peripheral T and B lymphocyte count, T helper : T suppressor ratio, as well as by impaired T suppressor function. These abnormalities may promote insulin antibody and other antibody production, contributing to overt diabetes mellitus development
Effect of adenosine and adenine nucleotides on blast transformation of rat thymocytes induced by concanavalin a
β Scribed by N. P. Dmitrienko; T. V. Goroshnikova; V. Yu. Umanskii; A. M. Bukhanevich
- Publisher
- Springer US
- Year
- 1982
- Tongue
- English
- Weight
- 326 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0007-4888
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## Abstract The immediate chemiluminescence (CL) response to concanavalin A (Con A) of rat thymocytes is enhanced 10 to 20βfold when the cells are preincubated in serumβfree medium for 5β20 h. During this period, multiple encounters between lymphocytes and macrophages occur which morphologically ap
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