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Effect of addition of ‘carrier’ DNA during transient protein expression in suspension CHO culture

✍ Scribed by Ketaki Pradhan,Mugdha Gadgil


Book ID
126354248
Publisher
Springer
Year
2012
Tongue
English
Weight
381 KB
Volume
64
Category
Article
ISSN
0920-9069

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Cultured mammalian cells, particularly Chinese hamster ovary (CHO) cells, are widely exploited as hosts for the production of recombinant proteins, but often yields are limiting. Such limitations may be due in part to the misfolding and subsequent degradation of the heterologous proteins. Consequent