Effect of actinomycin D and puromycin on the conversion of cholesterol into bile acids in bile fistula rats Bile acids and steroids 206
β Scribed by K. Einarsson; G. Johansson
- Book ID
- 115900746
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- English
- Weight
- 312 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0014-5793
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π SIMILAR VOLUMES
Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac
Bile acid synthesis is thought to be regulated by a negative feedback mechanism which is presumably dependent upon the flux of bile acids in the enterohepatic circulation. To characterize further the role of bile acids in regulation of bile acid synthesis, we have administered pure taurine or glycin
were prepared by using a sulfur trioxide complex (Aldrich, Milwaukee, Wis.) as described previously (Donovon, J. M. et al., Gastroenterology 1984; 84:1046, Abstract). When sulfation was complete (all the hydroxyl groups were sulfated), the purity of sulfated bile acids was better than 96% as checked