Effect of Acetazolamide (Diamox®) on tear secretion
✍ Scribed by E. J. Agtmaal; L. Thörig; N. J. Haeringen
- Publisher
- Springer-Verlag
- Year
- 1985
- Tongue
- English
- Weight
- 178 KB
- Volume
- 59
- Category
- Article
- ISSN
- 0012-4486
No coin nor oath required. For personal study only.
✦ Synopsis
The side effects of acetazolamide (Diamox | on lacrimation were measured in rats by means of the cotton-thread tear test. After a daily oral 1-mg dose (administered for five days), comparable to the dose used for adult humans on a drug-to-bodyweight basis, tear production remained unaffected but the lacrimal peroxidase secretion decreased by 60% of the baseline level. After withdrawal of acetazolmnide the peroxidase secretion returned to the baseline level.
📜 SIMILAR VOLUMES
Tear secretion may be influenced by various (groups of) drugs. A survey will be given of drug-induced changes in tear secretion and their clinical consequences.
## Abstract The effect of blending a short and a long chain prepolymer, i.e. the effect of biomodality, and that of concentration of the crosslinker on mechanical properties has been investigated. The content of short chain prepolymer was varied from 0 to 80 wt.‐%. Different concentrations of cross