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Effect of a vitamin D3 analogue on the growth, differentiation, cell cycle, and retinoblastoma protein of cultured normal human keratinocytes

โœ Scribed by Kobayashi, T.; Hashimoto, K.; Yoshikawa, K.


Book ID
122895233
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
128 KB
Volume
8
Category
Article
ISSN
0923-1811

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Calcipotriol (MC 903), a novel vitamin D
โœ K. Kragballe; I. L. Wildfang ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 412 KB

The hormonally active form of vitamin D3, 1,25-dihydroxy vitamin D3 [1,25-(OH)2-D3; calcitriol], regulates the differentiation and proliferation of epidermal keratinocytes in vitro. MC 903 (calcipotriol) is a novel vitamin D3 analogue which is at least 100 times less potent than 1,25-(OH)-2-D3 in it