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Effect of a new fluorinated quinolone (ofloxacin) on the chemiluminescence of phagocytosing human neutrophils

✍ Scribed by Aquilini, Donatella ;Bartoloni, Alessandro ;Paradisi, Franco

Publisher
John Wiley and Sons
Year
1989
Weight
165 KB
Volume
3
Category
Article
ISSN
0884-3996

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✦ Synopsis

We measured the chemiluminescence (CL) of human neutrophils (PMNLs) exposed to different concentrations of ofloxacin (2, 4, and 6pg/ml) readily achievable in therapy. CL reaction during zymosan phagocytosis by PMNLs obtained from human healthy volunteers was registered in a computer-linked LKB 1251 luminometer. Ofloxacin did not induce significant variations on the respiratory burst of PMNLs.

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