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Effect of a myosin light chain kinase inhibitor, wortmannin, on neurotransmitter release at the synapse formed in culture

โœ Scribed by Mochida, Sumiko; Nonomura, Yoshiaki; Kobayashi, Haruo


Book ID
121890307
Publisher
Elsevier Science
Year
1992
Weight
114 KB
Volume
17
Category
Article
ISSN
0921-8696

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Effects of a myosin light chain kinase i
โœ Makoto Takayama; Hiroshi Ozaki; Hideaki Karaki ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› Springer-Verlag ๐ŸŒ English โš– 870 KB

Biochemical studies have shown that wortmannin is an inhibitor of myosin light chain (MLC) kinase (Nakanishi et al. (1992) J. Biol. Chem. 267: 2157-2163). To investigate the role of MLC kinase in smooth muscle contractions, we examined the effects of wortmannin on isolated smooth muscles of the rat