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Effect of a Monoclonal Antibody to PCSK9 on LDL Cholesterol

✍ Scribed by Stein, Evan A.; Mellis, Scott; Yancopoulos, George D.; Stahl, Neil; Logan, Douglas; Smith, William B.; Lisbon, Eleanor; Gutierrez, Maria; Webb, Cheryle; Wu, Richard; Du, Yunling; Kranz, Therese; Gasparino, Evelyn; Swergold, Gary D.


Book ID
120525749
Publisher
Massachusetts Medical Society
Year
2012
Tongue
English
Weight
617 KB
Volume
366
Category
Article
ISSN
0096-6762

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Effect of a Monoclonal Antibody to PCSK9
✍ Sullivan, David; Olsson, Anders G.; Scott, Rob; Kim, Jae B.; Xue, Allen; Gebski, πŸ“‚ Article πŸ“… 2012 πŸ› American Medical Association 🌐 English βš– 290 KB

## Context: An estimated 10% to 20% of patients cannot tolerate statins or adequate doses to achieve treatment goals. plasma proprotein convertase subtilisin/kexin type 9 (pcsk9) binds to low-density lipoprotein (ldl) receptors, promoting their degradation and increasing ldl cholesterol levels. in