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Effect of a Monoclonal Antibody to PCSK9 on Low-Density Lipoprotein Cholesterol Levels in Statin-Intolerant Patients

โœ Scribed by Sullivan, David; Olsson, Anders G.; Scott, Rob; Kim, Jae B.; Xue, Allen; Gebski, Val; Wasserman, Scott M.; Stein, Evan A.

Book ID
118203831
Publisher
American Medical Association
Year
2012
Tongue
English
Weight
290 KB
Volume
308
Category
Article
ISSN
0098-7484

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๐Ÿ“œ SIMILAR VOLUMES

Effect of a Monoclonal Antibody to PCSK9
Effect of a Monoclonal Antibody to PCSK9 on Low-Density Lipoprotein Cholesterol Levels in Statin-Intolerant Patients
โœ Sullivan, David; Olsson, Anders G.; Scott, Rob; Kim, Jae B.; Xue, Allen; Gebski, ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› American Medical Association ๐ŸŒ English โš– 290 KB

## Context: An estimated 10% to 20% of patients cannot tolerate statins or adequate doses to achieve treatment goals. plasma proprotein convertase subtilisin/kexin type 9 (pcsk9) binds to low-density lipoprotein (ldl) receptors, promoting their degradation and increasing ldl cholesterol levels. in