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Ecotoxicological applications and significance of the comet assay

✍ Scribed by Jha, A. N.

Book ID
111654972
Publisher
Oxford University Press
Year
2008
Tongue
English
Weight
415 KB
Volume
23
Category
Article
ISSN
0267-8357

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The comet assay (single-cell gel electrophoresis), which measures DNA strand breaks at the level of single cells, is very easily applied to human lymphocytes, and therefore lends itself to human biomonitoring studies. For the examination of DNA base oxidation (a specific marker of oxidative damage),