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Echogenicity of the substantia nigra in Parkinson's disease and its relation to clinical findings

✍ Scribed by Daniela Berg; Christiane Siefker; Georg Becker

Publisher
Springer
Year
2001
Tongue
English
Weight
203 KB
Volume
248
Category
Article
ISSN
0340-5354

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## Abstract ## Background: Substantia nigra hyperechogenicity assessed by transcranial sonography is a typical finding in up to 90% of patients with idiopathic Parkinson's disease, although its value as a surrogate marker for disease progression in Parkinson's disease is controversial. ^123^I‐FP‐C

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## Abstract Transcranial sonography (TCS) reveals abnormal spatial extension of substantia nigra (SN) echogenicity in a high proportion of patients with Parkinson's disease (PD). It has been proposed that this abnormality represents a structural trait that is mechanistically distinct from degenerat