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Morphometry of the human substantia nigra in ageing and Parkinson’s disease

✍ Scribed by Gay Rudow; Richard O’Brien; Alena V. Savonenko; Susan M. Resnick; Alan B. Zonderman; Olga Pletnikova; Laura Marsh; Ted M. Dawson; Barbara J. Crain; Mark J. West; Juan C. Troncoso

Publisher: Springer-Verlag
Year: 2008
Tongue: English
Weight: 531 KB
Volume: 115
Category: Article
ISSN: 0001-6322
DOI: 10.1007/s00401-008-0352-8

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## Abstract ## Background: Substantia nigra hyperechogenicity assessed by transcranial sonography is a typical finding in up to 90% of patients with idiopathic Parkinson's disease, although its value as a surrogate marker for disease progression in Parkinson's disease is controversial. ^123^I‐FP‐C