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Echo-planar MR imaging of human brain oxygenation changes

✍ Scribed by Michael K. Stehling; Franz Schmitt; Ralf Ladebeck

Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
394 KB
Volume
3
Category
Article
ISSN
1053-1807

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✦ Synopsis

Abstract

Echo‐planar magnetic resonance (MR) imaging was used to observe signal intensity changes in the human brain during hypoxia. Increasing arterial blood levels of deoxyhemoglobin (0%–42%) during prolonged apnea were monitored with a pulse oximeter and correlated with gray matter and white matter signal attenuation of 13% and 20%, respectively. The results suggest the possibility of using deoxyhemoglobin boluses as a physiologic, intravascular susceptibility contrast agent for assessment of local cerebral oxygen utilization.

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