Easy cleavage of C′-terminal iminoacids from peptide acids through acidic hydrolysis
✍ Scribed by AUWERA, C. ;ANTEUNIS, M.J.O.
- Book ID
- 115098739
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 397 KB
- Volume
- 31
- Category
- Article
- ISSN
- 0367-8377
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📜 SIMILAR VOLUMES
A new strategy for solid-phase synthesis of C-terminal peptide amides based on the use of N-tetrachlorophthaloyl protected amino acids with acid-labile side-chain protection is described.
In order to eliminate the problems associated witb the use of alkali during peptide synthesis, a systematic investigation was catried out to lengthen pe tide chains by cou ling N-protected pentachlorophenyl active esters of a d n o acix and peptides w d amino acids and peptides, C-protected by dicyd
## Abstract The widespread occurrence of the neutral loss of one to six amino acid residues as neutral fragments from doubly protonated tryptic peptides is documented for 23 peptides with individual sequences. Neutral loss of amino acids from the N‐terminus of doubly charged tryptic peptides result