Easily Searched Protein Folding Potentials
โ Scribed by Gordon M. Crippen
- Book ID
- 115627458
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 312 KB
- Volume
- 260
- Category
- Article
- ISSN
- 0022-2836
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
We outline a general strategy for determining the effective coarse-grained interactions between the amino acids of a protein from the experimentally derived nativestate structures. The method is, in principle, free from any adjustable or empirically determined parameters, and it is tested on simple
Pairwise interaction models to recognize native folds are designed and analyzed. Different sets of parameters are considered but the focus was on 20 ุ 20 contact matrices. Simultaneous solution of inequalities and minimization of the variance of the energy find matrices that recognize exactly the na