## Abstract Signaling complexes and networks are being intensely studied in an attempt to discover pathways that are amenable to therapeutic intervention. A challenge in this search is to understand the effect that the modulation of a target will have on the overall function of a cell and its surro
Effective protein folding in simple random search
β Scribed by Taiji Imoto
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2000
- Tongue
- English
- Weight
- 78 KB
- Volume
- 58
- Category
- Article
- ISSN
- 0006-3525
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## Abstract The influences of temperature, friction, and random forces on the folding of protein A have been analyzed. A series of allβatom molecular dynamics folding simulations with the Amber ff99 potential and Generalized Born solvation, starting from the fully extended chain, were carried out f