Early tumor and leukemia response to alkyl-lysophospholipids in a phase I study
β Scribed by Dr Wolfgang E. Berdel; Hermann Schlehe; Ulrich Fink; Berthold Emmerich; Peter A. Maubach; Hans P. Emslander; Severin Daum; Johann Rastetter
- Publisher
- John Wiley and Sons
- Year
- 1982
- Tongue
- English
- Weight
- 727 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
In a phase I study a cytotoxic activity in the serum of a tumor patient given infusions of synthetic alkyl-lysophospholipid has been demonstrated. Serum samples collected after ALP infusions inhibited 3H-thymidine incorporation by human leukemic cells to an extent that correlated to the dose of ALP
## Background: Early response to therapy is defined as the initial response prior to day 28 of treatment, the conventional time of marrow evaluation. the number of reports linking early response to therapy with the ultimate outcome of childhood acute lymphoblastic leukemia is substantial and growin
## Abstract ## Background Canavan disease is a rare leukodystrophy with no current treatment. rAAVβASPA has been developed for gene delivery to the central nervous system (CNS) for Canavan disease. This study represents the first use of a viral vector in an attempt to ameliorate a neurodegenerativ
## Abstract ## Background It has been proposed that objective cognitive testing provides additional information to that collected via adverse event (AE) recordings. However, in clinical trials of compounds with potentially negative effects on cognition, the results of cognitive testing may overlap