We read with interest the recent short report titled "Conduction Block in Vasculitic Neuropathy" by Drs. Mohamed et al. (Muscle Nerve 1998;21:1084-1088). The chronic 2-year history and clinical findings of prominent ataxia, symmetric sensory loss, and weakness in their patient is more typical of an
Early electrophysiologic changes in conduction block
β Scribed by Dr. W. Trojaborg
- Publisher
- John Wiley and Sons
- Year
- 1978
- Tongue
- English
- Weight
- 324 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Fibrillation potentials and positive sharp waves were recorded in the paralyzed muscles of 31 patients with a conduction block of more than 14 days' duration. In 75% of the muscles, these effects were attributed to axonal damage in addition to the local demyelinating block, this conclusion being based on changes in the properties of the motor unit found electromyographically when recovery had taken place. In the remaining 25% of the muscles, the denervationβlike activity was thought to be an effect of the local demyelinating block alone. The delay of the sensory action potential recorded above the presumed site of nerve compression most likely arises from a block of the largest myelinated nerve fibers. This assumption is based on the fact that the amplitudes of the fastestβ and the slowerβconducted components in the patients differed little from corresponding components in the normal nerve.
π SIMILAR VOLUMES
Vasculitis involving peripheral nerves usually presents as an acute asymmetrical axonal neuropathy. We report a 67-year-old man with a symmetrical subacute neuropathy in which nerve conduction studies showed prominent conduction block, a finding indicative of demyelination. Sural nerve biopsy showed
The predominant electrophysiologic feature of vasculitic mononeuropathy multiplex is axonal loss. Electrophysiologic findings interpreted as conduction block have, however, also been reported to occur in neuropathy secondary to necrotizing vasculitis. We report 3 patients with mononeuropathy multipl