We read with interest the recent short report titled "Conduction Block in Vasculitic Neuropathy" by Drs. Mohamed et al. (Muscle Nerve 1998;21:1084-1088). The chronic 2-year history and clinical findings of prominent ataxia, symmetric sensory loss, and weakness in their patient is more typical of an
Conduction block in vasculitic neuropathy
β Scribed by Armin Mohamed; Leo Davies; John David Pollard
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 574 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0148-639X
No coin nor oath required. For personal study only.
β¦ Synopsis
Vasculitis involving peripheral nerves usually presents as an acute asymmetrical axonal neuropathy. We report a 67-year-old man with a symmetrical subacute neuropathy in which nerve conduction studies showed prominent conduction block, a finding indicative of demyelination. Sural nerve biopsy showed a vasculitic neuropathy with invasion of blood vessel walls by inflammatory cells and a mixture of nerve fiber loss and demyelination. The demyelination in this case was presumably a consequence of subinfarctive nerve ischemia.
π SIMILAR VOLUMES
The predominant electrophysiologic feature of vasculitic mononeuropathy multiplex is axonal loss. Electrophysiologic findings interpreted as conduction block have, however, also been reported to occur in neuropathy secondary to necrotizing vasculitis. We report 3 patients with mononeuropathy multipl