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Early changes of hepatitis B virus quasispecies during lamivudine treatment and the correlation with antiviral efficacy

✍ Scribed by Li Chen; Qian Zhang; De-min Yu; Mo-bin Wan; Xin-xin Zhang

Book ID: 116651818
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 670 KB
Volume: 50
Category: Article
ISSN: 0168-8278
DOI: 10.1016/j.jhep.2008.12.018

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Hepatitis B virus (HBV) reactivation has been described in cancer patients who received cytotoxic/immunosuppressive therapy and may result in liver damage of varying degrees of severity. There is no known effective treatment. Lamivudine, a nucleoside analogue, has been found to suppress HBV replicat