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Early aberrant DNA methylation events in a mouse model of acute myeloid leukemia

✍ Scribed by Miriam Sonnet,Rainer Claus,Natalia Becker,Manuela Zucknick…

Book ID
125405713
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
866 KB
Volume
6
Category
Article
ISSN
1756-994X

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## Abstract Hypermethylator phenotype, a propensity of tumors to incur nonrandom concurrent methylation, has been described in several tumors, including acute myeloid leukemia (AML). More recent studies identified methylation of other tumor suppressor genes, DAP‐kinase and SOCS1, singly in AML. We