E7-specific cytotoxic T cell tolerance in HPV-transgenic mice
โ Scribed by A. Borchers; J. Braspenning; J. Meijer; W. Osen; L. Gissmann; I. Jochmus
- Publisher
- Springer Vienna
- Year
- 1999
- Tongue
- English
- Weight
- 285 KB
- Volume
- 144
- Category
- Article
- ISSN
- 1432-8798
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Antigen-specific T cell tolerance can be induced by systemic injection of high-dose antigen. In particular, a single intravenous (i.v.) injection of influenza virus hemagglutinin peptide in HNT-TCR transgenic mice induces T cell tolerance through thymocyte apoptosis as well as anergy and deletion of