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E6a2 BCR-ABL fusion with BCR exon 5-deleted transcript in a Philadelphia positive CML responsive to Imatinib

✍ Scribed by Popovici, Cornel; Cailleres, Sylvie; David, Martine; Lafage-Pochitaloff, Marina; Sainty, Danielle; Mozziconacci, Marie-Joëlle


Book ID
120190686
Publisher
Informa plc
Year
2005
Tongue
English
Weight
119 KB
Volume
46
Category
Article
ISSN
1042-8194

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Since very few unusual BCR/ABL fusion transcripts in chronic myeloid leukemia have been reported, no clear evidence exists concerning their clinical and prognostic implications. We describe here a CML case with normal karyotype at standard cytogenetics and an atypical e6a2 BCR/ABL fusion transcript,