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E3 ubiquitin ligases for MHC molecules

✍ Scribed by Satoshi Ishido; Eiji Goto; Yohei Matsuki; Mari Ohmura-Hoshino

Book ID
108099617
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
261 KB
Volume
21
Category
Article
ISSN
0952-7915

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## Abstract The immune system uses several mechanisms of central and peripheral tolerance in order to prevent the activation of T lymphocytes toward self‐antigens. Although the importance of immune self‐tolerance has been established for a long time, some essential cellular and molecular mechanisms