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E3 ubiquitin ligases as T cell anergy factors

✍ Scribed by Mueller, Daniel L


Book ID
109921936
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
309 KB
Volume
5
Category
Article
ISSN
1529-2908

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E3 ubiquitin ligases in T-cell tolerance
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## Abstract The immune system uses several mechanisms of central and peripheral tolerance in order to prevent the activation of T lymphocytes toward self‐antigens. Although the importance of immune self‐tolerance has been established for a long time, some essential cellular and molecular mechanisms