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E2F6: a member of the E2F family that does not modulate squamous differentiation

✍ Scribed by Chung Fai Wong; Liam M. Barnes; Louise Smith; Claudia Popa; Magdalena M. Serewko-Auret; Nicholas A. Saunders


Book ID
116289235
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
588 KB
Volume
324
Category
Article
ISSN
0006-291X

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Several regulators of E2F transcriptional activity, including the retinoblastoma tumor suppressor (Rb) protein, p16 Ink4a , cyclin D1, and cyclin-dependent kinase 4, have been shown to be targets for genetic alterations that underlie the development of human cancers. Deregulation of E2F transcriptio