𝔖 Bobbio Scriptorium
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E2F transcription factors and cancer

✍ Scribed by Jaume Piulats; Gema Tarrasón


Book ID
110652332
Publisher
Springer Milan
Year
2001
Tongue
Spanish
Weight
88 KB
Volume
3
Category
Article
ISSN
1699-048X

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## Abstract Primarily, E2F factors such as E2F1, ‐2, and ‐3 stimulate cell‐cycle progression, while ARF tumor suppressor mediates growth suppression. The __ARF__ gene can be induced by oncogenic signal through activating E2F‐dependent transcription. In turn, ARF may target E2F for its degradation v