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E1.1 Telomerase gene amplification in relation to telomerase activity and expression in selected tumors


Book ID
119564096
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
107 KB
Volume
26
Category
Article
ISSN
0924-8579

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## BACKGROUND. Telomerase activation is thought to be crucial for the continued growth or progression of cancer cells. Three major subunits of human telomerase, human telomerase RNA (hTR), telomerase-associated protein (TP1), and human telomerase catalytic subunit (hTERT) have been identified rece

Telomerase activity and human telomerase
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## Background: Telomerase is a ribonucleoprotein enzyme that extends telomere specific repeats on the ends of chromosomes. telomerase activity has been detected frequently in various types of human tumors and has been associated with cell immortality and oncogenesis. human telomerase reverse transc