Telomerase activity has been found in a variety of malignant tumors but only rarely in benign tumors or normal tissues. In this study, we investigated telomerase activation in 37 ovarian tumors, including benign, borderline and malignant neoplasms. Telomerase activity was detected using the telomeri
β¦ LIBER β¦
E1.1 Telomerase gene amplification in relation to telomerase activity and expression in selected tumors
- Book ID
- 119564096
- Publisher
- Elsevier Science
- Year
- 2005
- Tongue
- English
- Weight
- 107 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0924-8579
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## BACKGROUND. Telomerase activation is thought to be crucial for the continued growth or progression of cancer cells. Three major subunits of human telomerase, human telomerase RNA (hTR), telomerase-associated protein (TP1), and human telomerase catalytic subunit (hTERT) have been identified rece
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## Background: Telomerase is a ribonucleoprotein enzyme that extends telomere specific repeats on the ends of chromosomes. telomerase activity has been detected frequently in various types of human tumors and has been associated with cell immortality and oncogenesis. human telomerase reverse transc