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E-cadherin-mediated adhesion inhibits ligand-dependent activation of diverse receptor tyrosine kinases

✍ Scribed by Qian, Xiaolan; Karpova, Tatiana; Sheppard, Allan M; McNally, James; Lowy, Douglas R


Book ID
110027549
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
514 KB
Volume
23
Category
Article
ISSN
0261-4189

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## Abstract Gap junction‐mediated intercellular communication (GJC) may play an important role in cell proliferation and transformation since GJC is inhibited by growth factors, oncogenes, tumor promoters, and carcinogens. We have studied inhibition of GJC by platelet‐derived growth factor‐BB (PDGF