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Dysregulation of BMP4 receptor trafficking and signaling in fibrodysplasia ossificans progressiva

✍ Scribed by Frederick S. Kaplan; Jennifer L. Fiori; Lourdes Serrano de la Peña; Jaimo Ahn; Paul C. Billings; Eileen M. Shore

Book ID
111635487
Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
109 KB
Volume
3
Category
Article
ISSN
1534-8644

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## Abstract Cell surface heparan sulfate proteoglycans (HSPGs) play important roles in morphogen gradient formation and cell signaling. Bone morphogenetic protein (BMP) signaling is dysregulated in fibrodysplasia ossificans progressiva (FOP), a disabling disorder of progressive heterotopic bone for