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Dyskinesias in normal squirrel monkeys induced by nomifensine and levodopa

✍ Scribed by Daniel M. Togasaki; Peter Protell; Louis C.S. Tan; J. William Langston; Donato A. Di Monte; Maryka Quik


Book ID
116784228
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
237 KB
Volume
48
Category
Article
ISSN
0028-3908

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The antidyskinetic potential of the glutamate NMDA receptor channel blocker amantadine was evaluated in four levodopa-primed parkinsonian monkeys using two different regimens (1.25 or 2.5 mg/kg administered subcutaneously twice daily for 3-6 days). When administered with a relatively low dose of lev