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Dysidiolide: A Novel Protein Phosphatase Inhibitor from the Caribbean Sponge Dysidea etheria de Laubenfels

โœ Scribed by Gunasekera, Sarath P.; McCarthy, Peter J.; Kelly-Borges, Michelle; Lobkovsky, Emil; Clardy, Jon


Book ID
126101557
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
103 KB
Volume
118
Category
Article
ISSN
0002-7863

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A b&act: Motuporin (I), a cyclic pcntapeptide that is a potent protein phosphatase-1 inhibitor and cylotoxin, has been isolated from the marine sponge Theonella swinhoei collected in Papua New Guinea. The structure of motuporjn was elucidafed by spectroscopic anaIysis and chemical degradation.