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Dysfunctional astrocytes as key players in the pathogenesis of central nervous system disorders

โœ Scribed by Jacques De Keyser; Jop P. Mostert; Marcus W. Koch


Book ID
118140828
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
757 KB
Volume
267
Category
Article
ISSN
0022-510X

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## Abstract Reactive astrocytes are one of the main impediments for axonal regeneration in the central nervous system of mammals. Using mice KO for GFAP and vimentin, we show that reinnervation occurs after an hemisection of the spinal cord, mainly through sprouting of controlateral intact serotoni