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Dysfunction of TGF-β1 signaling in Alzheimer’s disease: perspectives for neuroprotection

✍ Scribed by Filippo Caraci; Simona Spampinato; Maria Angela Sortino; Paolo Bosco; Giuseppe Battaglia; Valeria Bruno; Filippo Drago; Ferdinando Nicoletti; Agata Copani

Book ID: 106139955
Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 285 KB
Volume: 347
Category: Article
ISSN: 0302-766X
DOI: 10.1007/s00441-011-1230-6

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## Abstract Alzheimer's disease (AD) is a neurodegenerative disease that leads to a progressive loss of integrative and memory capacities of the brain. This is the predominant form of neurodegenerative dementia, with a growing prevalence of between 1 in 50 and 1 in 100 in North America. Numerous hy