Endothelial cell dysfunction in response
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Nadia Jahroudi; Jana Kitney; Joel S. Greenberger; Robert Bowser
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Article
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1998
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John Wiley and Sons
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English
β 928 KB
Previous reports have shown that exposure of vascular endothelial and smooth muscle cells to exogenous amyloid beta (Aβ€) peptide results in cell damage and toxicity via oxidative injury. In this study we demonstrate that overexpression of the amyloid precursor protein (APP) is toxic to bovine aortic