✦ LIBER ✦

Dynamics of transcriptional and translational processes in hepatocytes cultured in a collagen sandwich

✍ Scribed by James C. Y. Dunn; Ronald G. Tompkins; Martin L. Yarmush

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 499 KB
Volume: 41
Category: Article
ISSN: 0006-3592
DOI: 10.1002/bit.260410512

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Biotransformation of trichloroethylene i

Biotransformation of trichloroethylene in collagen gel sandwich cultures of rat hepatocytes

✍ Karen De Smet; Thomas Brüning; Meinolf Blaszkewicz; Hermann M. Bolt; Antoine Ver 📂 Article 📅 2000 🏛 Springer-Verlag 🌐 English ⚖ 150 KB

Long-term expression of differentiated f

Long-term expression of differentiated functions in hepatocytes cultured in three-dimensional collagen matrix

✍ Maria José Gómez-Lechón; Ramiro Jover; Teresa Donato; Xavier Ponsoda; Cristina R 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 311 KB 👁 2 views

Hepatocytes entrapped in collagen gel and cultured in serum-free conditions survived longer than cells cultured on plastic (5 days vs. 3 weeks), showed fewer signs of early cell senescence (no increase in c-fos oncoprotein expression), and maintained the expression of differentiated hepatic metaboli

Differential regulation of P-glycoprotei

Differential regulation of P-glycoprotein genes in primary rat hepatocytes by collagen sandwich and drugs

✍ Chow H. Lee 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 146 KB 👁 1 views

P-glycoprotein (Pgp) is a small family of plasma membrane proteins, which are capable of transporting substrates across cell membranes. Class I and II Pgp are able to transport drugs and have been shown to mediate multidrug resistance (MDR). Class III Pgp is a long chain phospholipid transporter and

Neural network in the transcription-tran

Neural network in the transcription-translation process in eukaryotic cells and viruses, a comparison

✍ J. Tohá; M. A. Soto 📂 Article 📅 1995 🏛 Springer 🌐 English ⚖ 350 KB

The importance of proline on long-term h

The importance of proline on long-term hepatocyte function in a collagen gel sandwich configuration: Regulation of protein secretion

✍ Jaegwan Lee; Jeffrey R. Morgan; Ronald G. Tompkins; Martin L. Yarmush 📂 Article 📅 1992 🏛 John Wiley and Sons 🌐 English ⚖ 743 KB

A serum-free culture system for primary hepatocytes which maintains stable high-level hepatocyte function for prolonged periods in culture has been developed. Isolated rat primary hepatocytes were cultured in serum-free media between two layers of gelled collagen in a sandwich configuration which re

Effects of dexamethasone on albumin and

Effects of dexamethasone on albumin and collagen gene expression in primary cultures of adult rat hepatocytes

✍ Douglas M. Jefferson; Dr. Lola M. Reid; Marie-Adele Giambrone; David A. Shafritz 📂 Article 📅 1985 🏛 John Wiley and Sons 🌐 English ⚖ 883 KB

To further our studies on collagen gene expression, we have evaluated the molecular basis for the finding that steroids decrease collagen synthesis in cultured hepatocytes. We studied the effects of dexamethasone on primary cultures of adult rat hepatocytes grown on tissue culture plastic in either