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Dynamics of the HIV Reverse Transcription Initiation Complex

✍ Scribed by Harada, Bryan T.; Liu, Shixin; Le Grice, Stuart F.J.; Zhuang, Xiaowei


Book ID
119206138
Publisher
Biophysical Society
Year
2010
Tongue
English
Weight
36 KB
Volume
98
Category
Article
ISSN
0006-3495

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Mechanistic aspects of HIV-1 reverse tra
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## Abstract During reverse transcription, the positive‐strand HIV‐1 RNA genome is converted into a double‐stranded DNA copy which can be permanently integrated into the host cell genome. Recent analyses show that HIV‐1 reverse transcription is a highly regulated process. The initiation reaction can