Dynamics of monocytes/macrophages and T lymphocytes in acutely rejecting rat renal allografts
β Scribed by V. Grau; Birgit Herbst; Birte Steiniger
- Publisher
- Springer-Verlag
- Year
- 1997
- Tongue
- English
- Weight
- 925 KB
- Volume
- 291
- Category
- Article
- ISSN
- 0302-766X
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Acute interstitial rejection (AIR) of renal allografts is accompanied by a characteristic peritubular increase in macrophages, which can be identified with the CD14 monoclonal antibody (mAb) WT14 in cryostat sections. Since frozen tissue is not always available, we tested whether this increase can a
## Abstract Acute rejection (AR) remains problematic in renal transplantation. As a marker, serum creatinine is limited, warranting a more effective screening tool. Raman spectroscopy (RS) can detect Tβcell activation with high sensitivity. In this study we explore its specificity. Seventyβfive ina