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Dynamics of lamivudine-resistant HBV mutants: a quasispecies analysis

โœ Scribed by Coralie Pallier; Laurent Castera; Alexandre Soulier; Daniel Dhumeaux; Jean-Michel Metreau; Jean-Michel Pawlotsky


Book ID
118565353
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
115 KB
Volume
36
Category
Article
ISSN
0168-8278

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The addition of adefovir dipivoxil (ADV) to ongoing lamivudine therapy is effective against lamivudine-resistant virus in patients with hepatitis B virus (HBV) infection. We studied 39 patients who received ADV added to lamivudine for breakthrough hepatitis. We determined early viral changes (12 wee