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Dynamic quasispecies analysis of YMDD mutants in patients with chronic hepatitis B resistant to lamivudine

โœ Scribed by L. Castera; C. Pallier; A. Soulier; D. Dhumeaux; J.M. Metreau; J.M. Pawlotsky


Book ID
117372538
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
167 KB
Volume
38
Category
Article
ISSN
0168-8278

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YMDD mutants in patients with chronic he
โœ Marie Matsuda; Fumitaka Suzuki; Yoshiyuki Suzuki; Akihito Tsubota; Norio Akuta; ๐Ÿ“‚ Article ๐Ÿ“… 2004 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 130 KB

## Abstract Hepatitis B virus (HBV) mutants with mutations in the YMDD motif of viral DNA polymerase/reverse transcriptase are described in patients infected with HBV who have not received lamivudine therapy, but their pathogenetic potential is not clear. These mutants were detected by the polymera